We develop methods for encapsulation of cells and design of micro tissues using self-folding polymer films. In our approach we use polymer bilayers consisting of polymers with different swelling properties. The cells are adsorbed on polymer bilayer, which rolls and forms the tube with cells inside. The tubes can be aligned and assembled together to form scaffolds for tissue engineering.

Selected publications

Stroganov, V.; Zakharchenko, S.; Sperling, E.; Meyer, A.K.; Schmidt, O.G; Ionov, L*. Biodegradable self-folding polymer films with controlled thermo-triggered folding, Advanced Functional Materials 2014, 24(27), 4357–4363. DOI: 10.1002/adfm.201400176

Reuther, C.; Tucker, R.; Ionov, L.; Diez, S. Programmable patterning of protein bioactivity by visible light, Nano Letters 2014, 14 (7), 4050–4057. DOI: 10.1021/nl501521q

Zakharchenko, S.; Puretskiy, N.; Stoychev, G.; Waurisch, C.; Hickey, S.G.; Eychmüller, A.; Sommer, J.U.; Ionov, L.* Stimuli-responsive hierarchically self-assembled 3D porous polymer-based structures with aligned pores Journal of Materials Chemistry B, 2013, 1, 1786-1793. DOI: 10.1039/C2TB00231K